Human Cytomegalovirus Enhances Chemokine Production by Lipopolysaccharide‐Stimulated Lamina Propria Macrophages

In vitro immunoglobulin synthesis by human intestinal lamina propria lymphocytes.

The concentration of IgG and IgA was measured in the supernatants of peripheral blood mononuclear cells and of cells harvested from the intestinal lamina propria, which were cultured in vitro in the presence or absence of mitogens. The lamina propria mononuclear cells were harvested by collagenase digestion of macroscopically normal mucosa from 10 fresh surgical resections for carcinoma. Secret...

Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.

Intestinal APCs are considered critical in maintaining the balance between the response against harmful pathogens and the induction of tolerance to commensal bacteria and food Ags. Recently, several studies indicated the presence of gut-specific APC subsets, which possess both macrophage and dendritic cell (DC) markers. These unique APC subsets play important roles in gut immunity, especially f...

Sulfated glycosaminoglycans in human vocal fold lamina propria.

INTRODUCTION The distribution, concentration and function of glycosaminoglycans in the various vocal fold tissues are still unclear. OBJECTIVE To evaluate the distribution and concentration of sulfated glycosaminoglycans in different layers of the human vocal fold according to gender and age. METHODS We used 11 vocal folds obtained from cadavers (7 men and 4 women) with no laryngeal lesion,...

Production of epithelial cell growth factors by lamina propria mononuclear cells.

The effects of lamina propria mononuclear cell culture supernatant on epithelial cell DNA synthesis were studied using cells isolated from patients with inflammatory bowel disease and normal controls. Supernatants from resting and phytohaemagglutinin stimulated cells were studied and supernatants that strongly promoted DNA synthesis were pooled, and growth factor activity partially characterise...

Lamina Propria CCL25-Deficient Intestinal Epithelium and CD8 Lymphocytes in Chemokine Impaired Accumulation of Antigen-Specific